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POS-272 DIFFERENTIAL EFFECTS OF ENDOTHELIN ETA RECEPTOR BLOCKADE ON VASCULAR CALCIFICATION AND RENAL INJURY IN RATS WITH CHRONIC KIDNEY DISEASE

Kidney international reports(2021)

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Abstract
Endothelin ETA receptor blockade has been shown to reduce arterial stiffness and calcification without affecting renal function in a rat model of chronic kidney disease (CKD). In the present study, we investigated the differential effects of ETAreceptor blockade on vascular calcification and renal injury in CKD rats.
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