Sars-Cov-2 Infection And Cancer Evidence For And Against A Role Of Sars-Cov-2 In Cancer Onset

BIOESSAYS(2021)

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摘要
Despite huge efforts towards understanding the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenesis, little is known about the long-term consequences of the disease. Here, we critically review existing literature about oncogenesis as a potential long-term effect of SARS-CoV-2 infection. Like other viral infections, SARS-CoV-2 may promote cancer onset by inhibiting tumor suppressor genes. We conclude that, although unlikely, such hypothesis cannot be excluded a priori and we delineate an experimental approach to address it.
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关键词
cancer, COVID-19, oncogenic viruses, SARS-CoV-2
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