Cardiac iron overload evaluation in thalassaemic patients using T2* magnetic resonance imaging following chelation therapy: a multicentre cross-sectional study

Eduardo Cerello Chapchap,Murilo Marques Almeida Silva,Reijane Alves de Assis,Lucila Nassif Kerbauy,Michelli da Silva Diniz,Laércio Alberto Rosemberg,Sandra Regina Loggetto,Aderson da Silva Araujo,Antonio Fabron Junior,Monica Pinheiro de Almeida Verissimo,Giorgio Roberto Baldanzi,Breno Pannia Esposito,Fernando Tricta, Merula Emmanoel Anargyrou Steagall,Claudia Ângela Galleni Di Sessa Vellozo,Kleber Yotsumoto Fertrin,Ronaldo Hueb Baroni,Nelson Hamerschlak

Hematology, Transfusion and Cell Therapy（2023）

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摘要

Chelation therapy significantly reduced cardiac siderosis in thalassaemic patients. In patients with moderate/severe liver iron concentration undergoing chelation therapy, ferritin levels and myocardium iron improved earlier than the liver siderosis.

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关键词

Iron overload,Thalassemia,Magnetic resonance imaging,Chelation therapy

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