Immune recognition of lysyl-tRNA synthetase and isoleucyl-tRNA synthetase by anti-OJ antibody-positive sera

Yoshinao Muro,Yasuhiko Yamano,Ken Yoshida,Yohsuke Oto,Kimiko Nakajima,Teruyuki Mitsuma,Shiori Kikuchi, Akihiro Matsumae,Mariko Ogawa-Momohara,Takuya Takeichi,Yasuhiro Kondoh,Masao Katayama,Yasuyuki Todoroki,Yoshiya Tanaka,Minoru Satoh,Masashi Akiyama

Journal of Autoimmunity（2021）

引用 12|浏览14

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摘要

•In vitro translated recombinant isoleucyl/lysyl tRNA synthetases were used in ELISA.•The ELISA results correlated well with anti-OJ antibody immunoprecipitation results.•In vitro translated recombinants were useful for detecting anti-OJ antibodies.

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关键词

Anti-OJ antibody,ELISA,Immunoprecipitation,in vitro transcription and translation,Isoleucyl-tRNA synthetase,Lysyl-tRNA synthetase

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