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Impaired antibody response to COVID-19 vaccination in patients with chronic myeloid neoplasms

Onima Chowdhury, Hannah Bruguier,Garry Mallett,Nikolaos Sousos, Kirsty Crozier, Caroline Allman,David Eyre,Sheila Lumley,Marie Strickland,Christina S Karali,Lauren Murphy,Alex Sternberg,Katie Jeffery,Adam J Mead,Andy Peniket,Bethan Psaila

BRITISH JOURNAL OF HAEMATOLOGY（2021）

Cited 38|Views25
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Abstract
The COVID-19 pandemic has had a severe impact on people with blood cancers. Patients with blood cancer are at an increased risk of poor outcomes after COVID-19 infection, with more severe infections and a higher case fatality rate (1-3), which may reflect immunocompromise due to their underlying disease and/or immunosuppressive treatments. As a result, regulatory approval and the subsequent rapid roll out of COVID-19 vaccines has been extremely well received by the blood cancer community.
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