The Abnormal Distribution of NK Cell Subsets Before HAART Treatment May Be Related to the Level of Immune Reconstitution in HIV Patient.

Suyu Sun,Wanzhong Kong,Xiaoya Cui,Yin Lin,Bibi Lu,Yong Pan, Jianping Huang,Xingzhong Hu

INTERNATIONAL IMMUNOPHARMACOLOGY（2021）

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摘要

•NK cell subsets in HIV patients are associated with disease progression.•Patients with low CD4+ T cells have higher expression of PD-1 and PS on NK cells.•The CD3−CD56−CD16+ NK cell subset before treatment is related with HAART efficacy.

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关键词

Natural killer cells,NK cell dysfunction,Highly active antiretroviral therapy,PD-1,PS

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