Evaluation Of Three Immunoassays For The Rapid Detection Of Sars-Cov-2 Antigens

Ilaria Baccani,Fabio Morecchiato,Chiara Chilleri,Chiara Cervini, Emanuele Gori,Daniela Matarrese,Andrea Bassetti, Manuela Bonizzoli,Jessica Mencarini,Alberto Antonelli,Gian Maria Rossolini

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE（2021）

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摘要

Three assays for SARS-CoV-2 antigen detection in nasopharyngeal swabs (Lumipulse (R) G SARS-CoV-2 Ag [LPG], STANDARD (TM) F COVID-19 Ag FIA [STF] and AFIAS COVID-19 Ag [AFC] were evaluated. Compared to RT-PCR, LPG, AFC and STF showed a variable sensitivity (87.9%, 37.5%, and 35.7%, respectively) and an overall high specificity (> 95%). (C) 2021 Elsevier Inc. All rights reserved.

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关键词

SARS-CoV-2, antigen, chemiluminescent assay, lateral flow immunofluorescence assay, COVID-19

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