Effect of corticosteroid dosing on outcomes in high-grade immune checkpoint inhibitor hepatitis.

Michael Li,Danny Wong,Alexander S Vogel,Jordan S Sack,Osama E Rahma,F Stephen Hodi,Stephen D Zucker,Shilpa Grover

Gastroenterology（2022）

引用 18|浏览5

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摘要

In patients with high-grade ICI hepatitis, initial treatment with 1 mg/kg/day methylprednisolone equivalents provides similar hepatitis outcomes with reduced risk of steroid-related complications when compared with higher-dose regimens.

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关键词

cancer,immune-related adverse event,immunotherapy,liver injury,steroid complications

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