Single-pot Enzymatic Synthesis of Cancer-Associated MUC16 O-glycopeptide Libraries and Multivalent Protein Glycoconjugates: a Step Towards Cancer Glycovaccines

Rui Freitas,Marta Relvas-Santos,Rita Azevedo,Janine Soares,Elisabete Fernandes,Beatriz Teixeira,Lucio Lara Santos,Andre M. N. Silva,Jose Alexandre Ferreira

New journal of chemistry（2021）

引用 5|浏览14

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摘要

Glycosyltransferases and nucleotide sugars are combined in single-pot settings to synthesize a library of cancer-associated MUC16 O-glycopeptides and multivalent protein glycoconjugates foreseeing future development of cancer glycovaccines.

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