Chemogenetic Engineering of Nitrobindin Toward an Artificial Epoxygenase

Daniel F. Sauer,Malte Wittwer,Ulrich Markel,Alexander Minges,Markus Spiertz,Johannes Schiffels,Mehdi D. Davari,Georg Groth,Jun Okuda,Ulrich Schwaneberg

CATALYSIS SCIENCE & TECHNOLOGY（2021）

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摘要

Chemogenetic engineering turned the heme protein nitrobindin into an artificial epoxygenase: MnPPIX was introduced and subsequent protein engineering increased the activity in the epoxidation of styrene derivatives by overall 7-fold.

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Metabolic Engineering

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