S-alkylated thiosemicarbazone derivatives: Synthesis, crystal structure determination, antimicrobial activity evaluation and molecular docking studies

•Synthesis and X-ray diffraction analysis of S-alkylthiosemicarbazones (T1-T10).•Unexpected formation of T8 containing pyrazole ring.•Evaluation of antibacterial, antifungal and antimycobacterial activities.•Determination of biofilm inhibition on P. aeruginosa and S. epidermidis biofilm positive strains.•Molecular docking supported quorum sensing inhibition.