The Use of Urine Mycobacterium tuberculosis Complex Polymerase Chain Reaction as a Predictive Factor for Recurrence and Progression After Intravesical Bacillus Calmette-Guérin Therapy in Patients with Non–muscle‑invasive Bladder Cancer

Satoru Muto,Yan Lu,Hisamitsu Ide,Raizo Yamaguchi,Keisuke Saito,Kousuke Kitamura,Yasuhiro Noma,Hiroki Koyasu,Hisashi Hirano,Takeshi Ashizawa,Shuji Isotani,Masayoshi Nagata,Shigeo Horie

European Urology Open Science（2021）

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摘要

In intermediate- or high-risk non–muscle-invasive bladder cancer patients after intravesical bacillus Calmette-Guérin (BCG) therapy, Mycobacterium tuberculosis complex polymerase chain reaction (MTC-PCR) positivity at least once was a significant prognostic factor in recurrence. A new adequate biomarker, urine MTC-PCR, is very useful noninvasive surrogate marker to predict the recurrence after BCG therapy.

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关键词

Bladder cancer,Bacillus Calmette-Guérin,Non–muscle invasive,Mycobacterium tuberculosis complex polymerase chain reaction

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