In vivo study of the bioavailability and metabolic profile of (poly)phenols after sous-vide artichoke consumption

Food Chemistry(2022)

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摘要
•A total of 76 (poly)phenol metabolites were quantifed after consumption of artichokes.•More than 80% of the phenolic metabolites were excreted after 4 h post-consumption.•The interindividual variability was high, especially for gut microbial metabolites.•3ʹ-Methylation exceeded 4ʹ-methylation in sous-vide artichoke (poly)phenol metabolism.•Hepatic beta-oxidation of 3ʹ,4ʹ-dihydroxycinnamic acid occurred, but was limited.
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关键词
Globe artichoke,(Poly)phenols,Caffeoylquinic acids,Metabolism,Bioavailability,UHPLC-MS/MS,COMT methylation
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