Global longitudinal strain as a prognostic marker in cardiac resynchronisation therapy: A systematic review

•Left ventricular global longitudinal strain (LV GLS) is a sensitive parameter that correlates with myocardial scar burden and fibrosis with potential value in CRT candidates.•First systematic review evaluating the existing evidence for the prognostic value of LV GLS in patients undergoing CRT implantation.•Despite significantly abnormal baseline GLS at CRT implantation, there is still a significant association between incrementally worse LV GLS at CRT implantation and prognostic outcomes on long-term follow-up.