Clinical Impact of Pathogenic Germline Variants in Pancreatic Cancer: Results From a Multicenter, Prospective, Universal Genetic Testing Study.

Pedro L S Uson,N Jewel Samadder,Douglas Riegert-Johnson,Lisa Boardman,Mitesh J Borad,Daniel Ahn,Mohamad B Sonbol,Douglas O Faigel,Norio Fukami,Rahul Pannala,Katie Kunze,Michael Golafshar,Margaret Klint,Edward D Esplin,Robert L Nussbaum,A Keith Stewart,Tanios Bekaii-Saab

Clinical and translational gastroenterology（2021）

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摘要

Universal multigene panel testing in PC reveals that 1 in 6 patients are carriers of PGV. Multigene germline testing should be used to aid in treatment selection, prognostication, and familial cancer counseling.

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