Post-training intra-basolateral complex of the amygdala infusions of clenbuterol enhance memory for conditioned place preference and increase ARC protein expression in dorsal hippocampal synaptic fractions

Neurobiology of Learning and Memory(2021)

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摘要
•Post-training activation of BLA β-adrenoceptors with clenbuterol enhances memory for an appetitive food conditioned place preference task (CPP).•Training on the CPP task upregulates dorsal hippocampal synaptic ARC protein expression.•Memory-enhancing intra-BLA administration of clenbuterol further upregulates dorsal hippocampal synaptic ARC protein expression following training on the CPP task.•De novo Dorsal hippocampal ARC protein expression is necessary for long-term memory of the CPP task.
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关键词
BLA,Appetitive learning,Local translation,Noradrenaline,Noradrenergic,Immediate early gene,Memory consolidation,Synaptic plasticity
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