IL-33 receptor expression on myeloid and plasmacytoid dendritic cells after allergen challenge in patients with allergic rhinitis

Ya-Qi Peng,De-Hua Chen,Zhi-Bin Xu, Shu-Bing Fang,Bi-Xin He,Xiao-Qing Liu,Cezmi A Akdis,Qing-Ling Fu

International Immunopharmacology（2021）

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摘要

•ST2 was highly expressed on mDCs and pDCs from patients with AR.•Allergen inhalation to patients with AR could upregulate the ST2 expression, as well as type 2 immune-related genes.•ST2+mDCs might have the potential to elicit allergic inflammation in response to IL-33.

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关键词

Myeloid dendritic cells,Plasmacytoid dendritic cells,IL-33,ST2,Allergic rhinitis,Allergen

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