Hypofractionated Radiation Therapy (HFRT) of Breast/Chest Wall and Regional Nodes in Locally Advanced Breast Cancer: Toxicity Profile and Survival Outcomes in Retrospective Monoistitutional Study

Sara De Matteis,Giuseppe Facondo,Maurizio Valeriani,Gianluca Vullo,Vitaliana De Sanctis,Anna Maria Ascolese,Barbara Campanella,Giovanna Scalabrino,Mattia Falchetto Osti

Clinical Breast Cancer（2022）

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摘要

•HFRT role in locally advanced breast cancer remains unknown.•HFRT showed excellent survival outcomes comparable to conventional fractionation•HFRT had excellent toxicity profile, with no acute nor late toxicities ≥G3•HFRT may be a valid therapeutic option in patients with locally advanced breast cancer

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关键词

Hypofractionated Radiotherapy,Radiotherapy dose fractionation,Breast-conserving surgery,Acute and Late Toxicity,Locally advanced breast cancer

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