Activation of 5-HT1 receptor in lateral habenula impaired contextual fear memory and hippocampal LTP in rat

Jingsheng Gu, Zhijie Hou, Xiaotao Zhou,Qinglei Wang,Yanmei Chen,Jichuan Zhang

Neuroscience Letters（2022）

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摘要

•Activation of 5-HT1 receptor in LHb impaired contextual fear memory in rats.•Activation of 5-HT1 receptor in LHb impaired hippocampal synaptic plasticity in rats.•Activation of 5-HT1 receptor in LHb increased anxiety- like behavior in rats.

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关键词

Serotonin receptor,Lateral Habenula,Long-Term potentiation,Fear conditioning

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