The uncinate fasciculus in individuals with and at risk for bipolar disorder: A meta-analysis

•Uses region-of-interest approach to examine properties of uncinate fasciculus.•Patients with bipolar disorder show lower uncinate fasciculus fractional anisotropy.•First-degree relatives do not show lower uncinate fasciculus fractional anisotropy.•Remains inconclusive whether aberrancies in uncinate fasciculus are an endophenotype.