Recombinant Human Endostatin Combined With Radiation Promotes Myocardial Fibrosis in Rat via TGF-beta 1/Smads/CTGF Signaling Pathway

O. W. Ouyang Weiwei, S. Fu,X. Zhao,S. F. Su,J. Zhang,D. Cao, Y. Wan, Q. Li,C. Zhao,M. Liu, F. Yang,W. Wang,Z. Ma,Y. Geng,B. Lu

International journal of radiation oncology, biology, physics（2021）

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摘要

The TGF-β1, Smad2/Smad3 and CTGF signaling pathways may be the common signaling pathways of myocardial fibrosis injury induced by rh-ES combined with radiation, which may be the target for the treatment of myocardial fibrosis by radiation.

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radiation promotes myocardial fibrosis,recombinant human endostatin combined

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