Genome-Scale CRISPR-Cas9 Knockout Screening in Nasopharyngeal Carcinoma for Radiosensitive and Radioresistant Genes

Z Ziyan,M Shen,L Jixi,L Kang,S Shi,W Chen,S Chen,Y Yin,Y Qin,M Kang

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS（2021）

引用 1|浏览7

暂无评分

摘要

We found nine genes through CRISPR/Cas9-mediated genome-wide knockout involved in the radiosensitivity or radioresistance of NPC cells: four genes for radiosensitivity, FBLN5, FAM3C, MUS81, and DNAJC17; two genes for radioresistance: CDKN2AIP, SP1, while TOMM20 and SNX22 are potential radioresistant genes, and CALD1 is a potential radiosensitive gene.

查看译文

关键词

Nasopharyngeal carcinoma,Radiosensitivity,Radiaoresistance,CRISPR-cas9,Functional gene

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要