Severity Assessment of Complex and Repeated Intracranial Surgery in Rats.

European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes(2023)

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摘要
Overall, cranial surgery of different complexity only transiently and rather mildly affects rat's well-being. Multiple measures assessment allows the differentiation of model-related motor disturbances in Parkinson's model from potentially pain-related conditions after tumor resection and electrode implantation.
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关键词
Animal well-being,Behavior,Neurosurgery,Principal component analysis,Refinement
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