JLX001 ameliorates cerebral ischemia injury by modulating microglial polarization and compromising NLRP3 inflammasome activation via the NF-κB signaling pathway

Hui-Jie Bian,Si-Yi Xu,Hui-Qin Li,Jun-Qiu Jia,Lei Ye,Shu Shu,Sheng-Nan Xia,Yue Gu, Xiong Zhu,Yun Xu,Xiang Cao

International Immunopharmacology（2021）

引用 11|浏览12

暂无评分

摘要

•JLX001 provides neuroprotection by modulating microglia polarization.•JLX001 inhibited NLRP3 activation after ischemic stroke.•JLX001 affects microglia polarization and NLRP3 activation by NF-κB pathways.

查看译文

关键词

Microglia,Inflammatory response,Ischemic stroke,NLRP3 inflammasome

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要