A mathematical model to evaluate the role of memory B and T cells in heterologous secondary dengue infection

Journal of Theoretical Biology(2022)

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摘要
•Memory B cell cloning is fundamental for dengue virus persistence when the basic reproduction number is less than one.•Memory T cell cloning corroborates the dengue virus control.•Successful dengue virus control depends on the levels of memory B and T cell cloning and the virus inoculation.
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关键词
Mathematical modeling,Antibody-dependent enhancement,Memory B cells,Memory T cells,Dengue virus
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