Integrative Analysis of the Inflammatory Bowel Disease Serum Metabolome Improves Our Understanding of Genetic Etiology and Points to Novel Putative Therapeutic Targets

Gastroenterology(2022)

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摘要
We integrated serum and stool metabolite levels with known genetic risk loci in patients with inflammatory bowel disease to shed light on potential metabolite mediators of disease.
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关键词
Inflammatory Bowel Disease,Metabolome,Differential Metabolite Abundance Analysis,Mendelian Randomization
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