Diagnostic accuracy of optical coherence tomography in the assessment of in vivo primary basal cell carcinoma resection margins prior to Mohs Micrographic Surgery

The diagnostic accuracy of optical coherence tomography (OCT) for in-vivo assessment of resection margins of basal cell carcinoma (BCC) prior to Mohs' Micrographic Surgery (MMS) remains unknown.(1) Therefore, we conducted a multicentre, case-control study with the objective to estimate sensitivity and specificity values. Included were patients with a biopsy proven primary BCC and an indication for MMS (2), who visited the dermatology outpatient clinic of Maastricht University Medical Centre+ or Mohs Klinieken in Hoorn, The Netherlands.