The cerebellum as a moderator of negative bias of facial expression processing in depressive patients

Anna Nakamura,Yukihito Yomogida,Miho Ota,Junko Matsuo,Ikki Ishida,Shinsuke Hidese,Hiroshi Kunugi

Journal of Affective Disorders Reports（2022）

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摘要

•Negative bias (NB) in emotion processing is an important aspect of MDD.•Neural basis of NB in facial expression processing in MDD was assessed.•Higher activation in posterior cerebellum was found to relate to higher NB in MDD.•Higher activation in the same area was related to a lower NB in the HC group.•This area might mediate biasing emotion processing by reflecting self-mood.

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关键词

Cerebellum,Facial expression processing,Functional MRI,Major depressive disorder,Negative bias

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