Principles Of Treatment Of Primary Immunodeficiencies

The current treatment strategy for patients with primary immunodeficiency disease is based on the prevention and aggressive treatment of infections, antibody replacement, and, when attainable, restoration of a functional immune system. This article will focus on the detailed management of the two most prominent groups of patients followed and treated by clinical immunologists - patients with profound T cell dysfunction (severe combined immunodeficiency, combined immunodeficiency) and patients with antibody deficiency (hypogammaglobulinemia, agammaglobulinemia).