Antiemetic Drugs As A Nasal Drug Delivery - A Review

Antiemetic drugs are used in the treatment of nausea and emesis. Development of novel delivery systems for antiemetic drugs, as an alternative to conventional preparations, is essential in terms of good patient compliance and improving bioavailability. The nasal route offers exclusive superiorities, such as rapid and high drug absorption, and high patient compliance. Consequently, a considerable amount of research has been carried out on the development of nasal delivery systems for antiemetic drugs. This review deals with the importance of nasal delivery of antiemetic drugs and the studies performed on this subject. The present review illustrates the studies conducted on the development of nasal delivery systems. Due to its better stability and bioavailability, the nasal route could be considered as an attractive alternative to oral and parenteral routes.