Increasing Recovery And Reproducibility Of Acidic Peptides In Rplc-Based Assays By Reducing Analyte-Surface Interactions

Robert E. Birdsall,Jacob Kellett,Ying Qing Yu,Weibin Chen

LC GC NORTH AMERICA（2020）

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摘要

Metal-ion mediated adsorption of sensitive analytes in LC-based assays can negatively impact data quality and assay robustness. Waters (TM) ACQUITY (TM) PREMIER Columns with MaxPeak (TM) HPS Technology are designed to minimize analyte-surface interactions while improving reproducibility, peak shape, and recovery of metal-surface sensitive analytes.

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