Ev71-Infected Hand-Foot-Mouth Disease With Multiple Organ Dysfunctions: A Case Study And Literature Review

Hand-foot-mouth disease (HFMD) is a common viral infection that usually affects infants and in some extreme cases can even be life threatening. The following study analyzed a case study of a HFMD patient (2-year-old child) complicated with multiple organ dysfunction. The patient suffered from fever, shiver, limb shaking and atypical rash and later developed pulmonary edema, pulmonary hemorrhage, multiple organ dysfunction, and was positive for blood EV71IgM antibody. After two successive bedside blood purifications and additional active treatments, organ functions were gradually restored. The patient was healed and discharged was done after approximately 3 months of hospitalization. Therefore, this report suggests that the immune injury may be one of the pathologies of severe HFMD. In addition, blood purification offers an effective treatment approach against HFMD.