Molecular Techniques In Immunopathology
IMMUNOPATHOLOGY IN TOXICOLOGY AND DRUG DEVELOPMENT: VOL 1, IMMUNOBIOLOGY, INVESTIGATIVE TECHNIQUES, AND SPECIAL STUDIES(2017)
摘要
Molecular pathology is a rapidly progressing field. As members of a multidisciplinary investigational team, pathologists are increasingly being asked to have a basic understanding of molecular techniques, their usefulness, and their limitations. The correlation of the morphologic phenotype with the cellular and gene based pathogenesis of disease lies within this realm. This chapter will focus on appropriate sample collection for molecular pathology as well as the utility of various molecular techniques as tools from for use in drug discovery and through development.
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关键词
In situ hybridization (ISH), Sample preparation, PCR analysis (Polymerase Chain Reaction), Next generation sequencing, Formalin fixed paraffin embedded (FFPE) tissue blocks
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