Intra-Tumor Heterogeneity In Acute Myeloid Leukemia (Aml): Results From A Real Life Cohort
BLOOD（2018）
摘要
Context. AML is an oligoclonal disease. Intratumoral genetic heterogeneity (ITH) is pervasive in cancers and has often been linked to poor outcome. Except in patients (pts) with complex karyotypes (Bochtler, J Clin Oncol 2013), the clinical relevance of ITH remains unknown in AML. We assessed ITH in a real-life AML cohort.
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