Neat synthesis of c-fused pyrroles and its application to macrolactamization
SYNTHETIC COMMUNICATIONS(2021)
摘要
The current study describes an efficient environmental benign synthetic route of N-aryl substituted c-fused pyrrole derivatives via neat approach. It also provides base-mediated intramolecular macrolactamization using amine ester amidation reaction and leads to fused diazocine-6(5H)-one with effective yields.
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关键词
Aza-Michael addition,c-fused pyrrole,diazocine-6(5H)-one,macrolactamization,neat reaction
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