Study On The Preparation Of Freeze-Dried Royal Jelly Fetal Anti-Aging Granules And Mechanism

Taking the queen fetus as the experimental object, the physical and chemical components of the queen fetus were determined, and the enzymatic hydrolysis process of the protein of the queen fetus Was optimized by using single-factor experiments and response surface analysis. Ultrafiltration, gel filtration and other methods Were used to isolate and purify the royal jelly fetus enzymolysis product, and the in vitro antioxidant method was used to measure the in vitro antioxidant activity of the royal jelly fetus protein hydrolysate, in order to obtain antioxidant peptides with application value. Provide a basis for the development and utilization of queen fetus protein resources. And the lyophilized royal queen fetal anti aging granules were prepared to observe the effect of anti-aging granules on the learning and memory ability of D-galactose-induced aging model mice. A metabolism research method based on 1H-NMR was used. Differential metabolites Were detected in the urine of aging model mice. D-galactose-induced aging model mice had cognitive dysfunction, which showed reduced learning and memory abilities, poor spatial location ability, and decreased memory. Anti aging particles can change the cognitive function of aging model mice and improve the learning and incinory ability of D-galactosc aging model mice. Anti-aging granules can improve the disturbance of energy metabolism, amino acid metabolism and inflanunatory response-related pathways in aging model mice induced by D-galactose.