Nocardia Farcinica Brain Abscess In A Multiple Myeloma Patient Treated With Proteasome Inhibitor: A Case Report And Review Of The Literature
BRAIN SCIENCES(2021)
摘要
Nocardia brain abscess is relatively rare, accounting for about 1-2% of all brain abscesses, and its mortality rate is three times higher than of other types of bacterial brain abscesses; thus, early diagnosis and treatment are essential. Nocardia brain abscess generally occurs in immunodeficient patients. We report a case of Nocardia farcinica brain abscess in a multiple myeloma patient treated with proteasome inhibitor (bortezomib and ixazomib), cyclophosphamide, and corticosteroid. The patient was treated with ceftriaxone and trimethoprim-sulfamethoxazole, together with drainage of the brain abscess. Regular brain MRI follow-ups showed that intracranial lesions were gradually absorbed and improved.
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关键词
multiple myeloma, proteasome inhibitor, Nocardia farcinica, brain abscess
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