A novel SPE-UHPLC-DAD method for the determination of fumagillin produced by Aspergillus fumigatus in cell culture media

Oskar Gonzalez,Ane Yaldebere,Xabier Guruceaga,Andoni Ramirez-Garcia,Aitor Rementeria,Rosa Maria Alonso

Microchemical Journal（2021）

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摘要

•Quantification of fumagillin produced by different strains of A. fumigatus.•First validated method applied to the quantification of fumagillin in cell culture.•Fast, simple and sensitive determination of fumagillin by SPE-UHPLC-DAD.•Useful method to study invasive aspergillosis.

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关键词

Fumagillin,A. fumigatus,SPE,UHPLC,RPMI-1640

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