Breast Cancer Characteristics In Mongolian And Disparities Of Ethnicities Among Chinese Patients

Purpose: This work was to analyze breast cancer (BC) characteristics of Mongolian patients, summarize main BC characteristics of minority ethnicities and compare with that of Mainland China. Methods: BC main characteristics of Mongolian and Han from Inner Mongolia of China from 2011 to 2014 were collected and analyzed. BC patients of Chinese from Central China and USA were enrolled for comparable analysis. BC characteristics of minority ethnicities from other reports of China were searched and compared with that of Mainland China. Results: There were no disparities of BC characteristics between Mongolian and Han in three groups of patients of China (Mongolian and Han patients in Inner Mongolia and Central China). BC characteristics of the three groups of China showed significant differences of that in Chinese American, including higher proportion of younger patients, larger tumor size, lymph node positive, regional stage, hormone receptor (HR) negative and human epidermal growth factor receptor 2 (HER2) positive (p<0.001) for China. BC characteristics were reported in only four minority ethnicities of China, including Hui, Uygur, Mongolian and Kazakh. Compared with Mainland China, main BC characteristics of the patients among Mongolian, Hui and Kazakh in China displayed similar patterns, but with distinct patterns with that of Uygur, including lower rates of localized stage, lymph node negative and ER positive. Conclusion: BC characteristics of Mongolian were similar with that of Han in China, but not for Chinese American. BC characteristics of Mongolian, Hui and Kazakh were similar with that of Mainland China, but not for Uygur patients.