Photocatalytic Degradation of Ciprofloxacin Pollutant and In-Vitro Cytotoxic Activity of Gold Nanoparticles Using Seed Extract of Abrus Precatorius

Synthesis of nanoparticles from plant extract is a very simple reliable, rapid, affordable and un-hazardous technique. In the present exploration, gold nanoparticles (Au NPs) were rapidly synthesized using seed extract of Abrus precatorius. The prepared nanomaterials were systematically proved by FTIR, UV–Visible, Powder-XRD, SEM, EDAX and TEM analyses. The formation of Au NPs was primarily identified by the colour change from yellow to purple within 5 min and which showed a surface Plasmon peak around 535 nm. The dimension of the gold nanoparticles was found to be in the range of 10–20 nm. The particles were poly-dispersed with a triangular, spherical and hexagonal shape. The gold nanoparticles were used to degrade the antibiotic drug ciprofloxacin (CIP) with an efficiency of above 95%. Moreover, the bio-synthesized gold nanoparticles had been assessed for their in-vitro cytotoxic activity on human breast cancer cells (MCF-7) lines. The colorimetric 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay was used to evaluate the Inhibitory Concentration (IC50) value. The IC50 value is 37 ± 1.5 µg/mL. In future, this can be used for breast cancer therapy.