Predicting The Differential Diagnosis Of Pneumonitis In Stage Iv Non-Small Cell Lung Cancer (Nsclc) Patients Treated With Immune Checkpoint Inhibitors (Icis) By Combining Clinical And Radiomic Features

F. Tohidinezhad,A. Traverso, I. Zhovannik, A. Romita,L. E. L. Hendriks,A-M. C. Dingemans,J. G. Aerts,G. Bootsma,J. F. Vansteenkiste,S. Hashemi, E. F. F. Smit,H. Gietema,D. De Ruysscher

ANNALS OF ONCOLOGY（2021）

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摘要

ICI-induced pneumonitis is a severe side effect occurring in 4-10% of the patients, requiring an appropriate diagnosis for management with steroids. The differential diagnosis between ICI-related (ICI-R) and other causes of pneumonitis (OP) remains challenging. We therefore developed a prediction model including clinical and radiomic parameters for the differential diagnosis of pneumonitis in stage IV NSCLC patients.

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关键词

immune checkpoint inhibitors,lung cancer,pneumonitis,non-small

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