Impact of Advanced Radiotherapy on Second Primary Cancer Risk in Prostate Cancer Survivors: A Nationwide Cohort Study.

Marie-Christina Jahreiß,Wilma D Heemsbergen, Bo van Santvoort,Mischa Hoogeman,Maarten Dirkx,Floris J Pos,Tomas Janssen, Andre Dekker,Ben Vanneste,Andre Minken,Carel Hoekstra,Robert J Smeenk,Inge M van Oort,Chris H Bangma,Luca Incrocci,Katja K H Aben

Frontiers in oncology（2021）

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摘要

SPC risk in patients with EBRT is increased and remained throughout the different EBRT eras. The risk of developing a SPC outside the pelvic area changed unfavorably in the AdvRT era. Prolonged follow-up is needed to confirm this observation. Whether this is associated with increased irradiated low-dose volumes and scatter, or other changes in clinical EBRT practice, is the subject of further research.

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advanced external beam radiotherapy,prostate cancer,second primary cancer,survivorship,three-dimensional conformal radiotherapy

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