Immunotherapeutic early-phase clinical trials and malignant gliomas: A single-center experience and comprehensive immunophenotyping of circulating leukocytes.

Matteo Simonelli,Pasquale Persico,Arianna Capucetti,Claudia Carenza,Sara Franzese,Elena Lorenzi,Angelo Dipasquale,Agnese Losurdo,Laura Giordano,Federico Pessina,Pierina Navarria,Letterio S Politi,Domenico Mavilio,Massimo Locati,Silvia Della Bella,Armando Santoro,Raffaella Bonecchi

Neuro-oncology advances（2021）

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摘要

A subgroup of EG patients achieved remarkably durable disease control. promoter methylation identifies patients who benefit more from immunotherapy. Monitoring dynamic changes of innate immune cell populations may help to predict clinical outcomes.

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关键词

circulating leukocytes,early-phase clinical trials,glioblastoma,gliomas,immunotherapy

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