The influence of CYP2R1 polymorphisms and gene–obesity interaction with hypertension risk in a Chinese rural population

Z Xu,D Zhang,J Lin, X Li, Y Liu,J Gao, Y Xue,Y Zhang, R Ding, G Huang, T Zhao, H Huang, C Gu,W Li

Nutrition, Metabolism and Cardiovascular Diseases（2022）

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摘要

•CYP2R1 gene polymorphisms were associated with vitamin D deficiency.•CYP2R1 rs12794714 variant was related to hypertension risk under the dominant model.•There was a significant interaction between rs12794714 variant and obesity on hypertension risk.

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关键词

Hypertension,CYP2R1,Obesity,Interaction

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