The Effect of Reduced Dose Recombinant Tissue Plasminogen Activator on Clinical Results in Acute Pulmonary Embolism: Case Series

Background: Acute Pulmonary Embolism (APE) is a life-threatening condition at which time control is important. The purpose of this case series is to evaluate the post-treatment prognosis and treatment-related complications in cases who are hemodynamically stable, but in echocardiography findings, considered as submassive APE due to right ventricular dilatation or acute troponin T, pro-Brain Natriuretic Peptide (pro-BNP) enzyme elevation, so given alteplase (rt-PA) in reduced dose (50 mg/2h).