Title: Sex and Circuit Specific Dopamine Transporter Regulation Underlies Unique Behavioral Trajectories of Functional SLC6A3 Coding Variation Running Title (50 Characters): Sexual dimorphism in DAT Val559 mice Authors/Affiliations

Adele Stewart PhD1,3, Felix P. Mayer PhD1, Raajaram Gowrishankar PhD1, Gwynne L. Davis PhD1, Lorena B. Areal PhD1, Paul J. Gresch PhD1,3, Rania M. Katamish1, Rodeania Peart2, Samantha E. Stilley1, Keeley Spiess1, Maximilian J. Rabil1, Faakhira A. Diljohn2, Angelica E. Wiggins1, Roxanne A. Vaughan PhD4, Maureen K. Hahn PhD1,3, Randy D. Blakely PhD1,3,* 1Department of Biomedical Science, 2Wilkes Honors College, and 3Brain Institute, Florida Atlantic University, Jupiter, FL. 4Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota.