Polymer slab waveguides for the optical detection of nanoparticles in evanescent field based biosensors
Proceedings of SPIE(2014)
摘要
We present a polymer optical waveguide integration technology for the detection of nanoparticles in an evanescent field based biosensor. In the proposed biosensor concept, super-paramagnetic nanoparticles are used as optical contrast labels. The nanoparticles capture target molecules from a sample fluid and bind to the sensor surface with biological specificity. The surface-bound nanoparticles are then detected using frustration of an evanescent field. In the current paper we elaborate on the polymer waveguides which are used to generate a well-defined optical field for nanoparticle detection.
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关键词
biosensor,evanescent field,nanoparticle detection,polymer waveguide
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