Relationship of alcohol use and facial flushing to blood pressure and HbA1c among Cambodian populations with dysglycemia in the U.S. and in Cambodia
DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS(2022)
摘要
Background and aims: Facial flushing after drinking alcohol, common among Asians, is a phenotype for genes involved in alcohol metabolism. Methods: We investigated cross-sectional associations between flushing, alcohol use, blood pressure (BP) and HbA1c among (n = 287) Cambodians with dysglycemia in Cambodia and in the U.S. Participants were categorized as Abstainers, Flushers who drink, or Non-flushers who drink. Results: Flushers and Non-flushers had similar alcohol use. Flushers had higher BP than Non-flushers and Abstainers, even after controlling for confounders. Findings were similar across countries. Drinkers had higher HbA1c than Abstainers. Conclusions: Future research should examine whether reducing alcohol improves cardiometabolic outcomes. (c) 2021 Diabetes India. Published by Elsevier Ltd. All rights reserved.
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关键词
Facial flushing, Alcohol, Blood pressure, HbA1c, Type 2 diabetes, Cambodia
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