Injury to thalamocortical projections following traumatic brain injury results in attractor dynamics for cortical networks

Progress in Neurobiology(2022)

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摘要
•Consciousness is associated with complex cortical activity.•Injury to thalamo-prefrontal connections leads to cortical attractor dynamics.•This attractor generates deterministic and predictable cortical activity.•The number of available cortical states in this attractor regime is limited.•Thalamic input is critical to cortical flexibility required for consciousness.
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关键词
Traumatic brain injury (TBI),Recovery of consciousness,Thalamocortical loop,Phase space reconstruction,Gaussian processes,Yule-Simon processes
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