Simultaneous determination of ivermectin, clorsulon and their related substances in an injectable finished product by a stability-indicating RP-HPLC method

•Determination of ivermectin and clorsulon using a single HPLC method.•Utilization of rapid and automated chromatographic method development tools.•Method was found to be sensitive, accurate, reproducible, and robust.•Stability-indicating capability of the method was demonstrated.